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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IMMT Antibody (C-term)   

IMMT Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IMMT Antibody (C-term) AP2931B
    Western blot analysis of IMMT Antibody (C-term) (Cat. #AP2931b) in Hela cell line lysates (35ug/lane). IMMT (arrow) was detected using the purified Pab.
  • WB - IMMT Antibody (C-term) AP2931B
    Western blot analysis of IMMT (arrow) using rabbit polyclonal IMMT Antibody (C-term) (Cat. #AP2931b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the IMMT gene (Lane 2) .
  • FC - IMMT Antibody (C-term) AP2931B
    Flow cytometric analysis of hela cells using IMMT Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • IHC-P - IMMT Antibody (C-term) AP2931B
    IMMT Antibody (C-term) (Cat. #AP2931b) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IMMT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16891
Other Accession Q8CAQ8, NP_006830
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 83678 Da
Antigen Region 700-729 aa
Additional Information
Gene ID 10989
Other Names MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, Mitochondrial inner membrane protein, Mitofilin, p87/89, IMMT, HMP, MIC60, MINOS2
Target/Specificity This IMMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 700-729 amino acids from the C-terminal region of human IMMT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIMMT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HMP, MIC60, MINOS2
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Cellular Location Mitochondrion inner membrane; Single-pass membrane protein
Research Areas
Citations (0)

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Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology.


Bernert,G.,, Proteomics 2 (12), 1752-1757 (2002)

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Cat# AP2931B
(40 western blots)
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