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HNRPL Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HNRPL Antibody (Center) AP2950c
    Western blot analysis of HNRPL Antibody (Center) (Cat. #AP2950c) in HepG2, Jurkat cell line lysates (35ug/lane). HNRPL (arrow) was detected using the purified Pab.
  • WB - HNRPL Antibody (Center) AP2950c
    Western blot analysis of HNRPL (arrow) using rabbit polyclonal HNRPL Antibody (Center) (Cat. #AP2950c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HNRPL gene (Lane 2) .
  • IHC-P - HNRPL Antibody (Center) AP2950c
    Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with HNRPL Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - HNRPL Antibody (Center) AP2950c
    HNRPL Antibody (Center) (Cat. #AP2950c) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P14866
Other Accession Q8R081
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 64133 Da
Antigen Region 249-277 aa
Additional Information
Gene ID 3191
Other Names Heterogeneous nuclear ribonucleoprotein L, hnRNP L, HNRNPL, HNRPL
Target/Specificity This HNRPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human HNRPL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHNRPL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HNRPL
Function Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.
Cellular Location Nucleus, nucleoplasm. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs
Citations (0)

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HNRPL is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. L is associated with most nascent transcripts including those of the landmark giant loops of amphibian lampbrush chromosomes.


Hahm,B.,, FEBS Lett. 425 (3), 401-406 (1998)
Funke,B.,, Nucleic Acids Res. 24 (19), 3821-3828 (1996)

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$ 295.00
$ 99.00
Cat# AP2950c
(40 western blots)
Availability: In Stock
Bulk Size
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