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Phospho-MYC(T58) Antibody

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • DB - Phospho-MYC(T58) Antibody AP3325a
    Dot blot analysis of Phospho-MYC-T58 Pab (Cat.AP3325a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
  • WB - Phospho-MYC(T58) Antibody AP3325a
    Western blot analysis of Phospho-MYC-T58 Antibody in human TPA activated Hela cell line lysates. Phospho-MYC (arrow) was detected using the purified PAb. (0: without TPA; 1: 60ug/ml TPA, 15min; 2: 60ug/ml TPA, 30min; 3: 60ug/ml TPA, 45min; 4: 125ug/ml TPA, 15min; 5: 125ug/ml TPA, 30min; 6: 125ug/ml TPA, 45min; 7: 250ug/ml TPA, 15min; 8: 250ug/ml TPA, 30min; 9: 250ug/ml, 45min)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01106
Other Accession P09416, Q29031, P01108, P01109, Q2HJ27, P24793, Q63379, P03966, P04198, Q9PSJ0, P18444, P15171, Q7ZVS9, P52160, P06171, Q28566
Reactivity Human
Predicted Xenopus, Zebrafish, Chicken, Mouse, Rat, Bovine, Pig, Sheep
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48804 Da
Additional Information
Gene ID 4609
Other Names Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39
Target/Specificity This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
Dilution DB~~1:500
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPhospho-MYC(T58) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYC
Synonyms BHLHE39
Function Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Cellular Location Nucleus, nucleoplasm. Nucleus, nucleolus
Research Areas
Citations ( 0 )


MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.


Qi, Y., et al., Nature 431(7009):712-717 (2004).
Wilda, M., et al., Genes Chromosomes Cancer 41(2):178-182 (2004).
Dom, et al., Oncogene 23(44):7378-7390 (2004).
Pap, T., et al., Arthritis Rheum. 50(9):2794-2802 (2004).
Ozawa, N., et al., Endocrinology 145(9):4244-4250 (2004).

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$ 295.00
$ 99.00
Cat# AP3325a
(40 western blots)
Availability: In Stock
Bulk Size
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