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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PNPLA8 Antibody (N-term)   

PNPLA8 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PNPLA8 Antibody (N-term) AP4706a
    PNPLA8 Antibody (N-term) (Cat. #AP4706a) western blot analysis in Hela,K562 cell line lysates (35ug/lane).This demonstrates the PNPLA8 antibody detected the PNPLA8 protein (arrow).
  • FC - PNPLA8 Antibody (N-term) AP4706a
    PNPLA8 Antibody (N-term) (Cat. #AP4706a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NP80
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 88477 Da
Antigen Region 212-240 aa
Additional Information
Gene ID 50640
Other Names Calcium-independent phospholipase A2-gamma, Intracellular membrane-associated calcium-independent phospholipase A2 gamma, iPLA2-gamma, PNPLA-gamma, Patatin-like phospholipase domain-containing protein 8, iPLA2-2, PNPLA8, IPLA22, IPLA2G
Target/Specificity This PNPLA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the N-terminal region of human PNPLA8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPNPLA8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms IPLA22, IPLA2G
Function Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Cytoplasm, perinuclear region
Tissue Location Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart
Research Areas
Citations (0)

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PNPLA8 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function.


Harper, M.T., et al. J. Thromb. Haemost. 6(10):1819-1821(2008)
Wilson, P.A., et al. J. Lipid Res. 47(9):1940-1949(2006)
Murakami, M., et al. J. Biol. Chem. 280(14):14028-14041(2005)

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$ 295.00
$ 99.00
Cat# AP4706a
(40 western blots)
Availability: In Stock
Bulk Size
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