|Application ||WB, IHC-P, E|
|Calculated MW||40883 Da|
|Antigen Region||18-47 aa|
|Other Names||Partitioning defective 6 homolog gamma, PAR-6 gamma, PAR6D, PARD6G, PAR6G|
|Target/Specificity||This PAR6G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the N-terminal region of human PAR6G.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAR6G Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity).|
|Cellular Location||Cytoplasm. Cell membrane. Cell junction, tight junction|
|Tissue Location||Widely expressed, with a higher expression in fetal and adult kidney|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
PAR6G involved in asymmetrical cell division and cell polarization processes. PAR6G may play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Brajenovic, M., et al. J. Biol. Chem. 279(13):12804-12811(2004)
Kohjima, M., et al. Biochem. Biophys. Res. Commun. 299(4):641-646(2002)
Suzuki, A., et al. J. Cell Biol. 152(6):1183-1196(2001)
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