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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   AVIL Antibody (N-term)   

AVIL Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AVIL Antibody  (N-term) AP4756a
    Western blot analysis of AVIL Antibody (N-term) (Cat. #AP4756a) in K562 cell line lysates (35ug/lane). AVIL (arrow) was detected using the purified Pab.
  • IHC-P - AVIL Antibody  (N-term) AP4756a
    AVIL Antibody (N-term) (Cat. #AP4756a) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AVIL Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - AVIL Antibody  (N-term) AP4756a
    AVIL Antibody (N-term) (Cat. #AP4756a) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75366
Other Accession O88398
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 92027 Da
Antigen Region 176-204 aa
Additional Information
Gene ID 10677
Other Names Advillin, p92, AVIL
Target/Specificity This AVIL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the N-terminal region of human AVIL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAVIL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.
Cellular Location Cytoplasm, cytoskeleton. Cell projection. Cell projection, axon
Tissue Location Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus.
Research Areas
Citations (0)

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AVIL is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia.


Piana, S., et al. J. Mol. Biol. 375(2):460-470(2008)
Vermeulen, W., et al. Protein Sci. 13(5):1276-1287(2004)
Tumer, Z., et al. Gene 288 (1-2), 179-185 (2002)

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Cat# AP4756a
(40 western blots)
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