|Application ||WB, E|
|Calculated MW||37979 Da|
|Antigen Region||210-237 aa|
|Other Names||Torsin-1B, Torsin ATPase-1B, 364-, Torsin family 1 member B, TOR1B, DQ1|
|Target/Specificity||This TOR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-237 amino acids from the Central region of human TOR1B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TOR1B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity. May have a redundant function with TOR1A in non-neural tissues.|
|Cellular Location||Endoplasmic reticulum lumen. Nucleus membrane|
|Tissue Location||Widely expressed with low levels in brain.|
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Provided below are standard protocols that you may find useful for product applications.
TOR1B may serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins.
Kamm, C., et al. Neurology 67(10):1857-1859(2006)
Bahn, E., et al. Brain Res. 1116(1):112-119(2006)
Hewett, J.W., et al. J. Neurochem. 89(5):1186-1194(2004)
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