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>   home   >   Products   >   Primary Antibodies   >   WDR82 Antibody (N-term)   

WDR82 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - WDR82 Antibody (N-term) AP4812a
    Western blot analysis of WDR82 Antibody (N-term) (Cat. #AP4812a) in HepG2 cell line lysates (35ug/lane). WDR82 (arrow) was detected using the purified Pab.
  • IHC-P - WDR82 Antibody (N-term) AP4812a
    WDR82 Antibody (N-term) (Cat. #AP4812a) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the WDR82 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - WDR82 Antibody (N-term) AP4812a
    WDR82 Antibody (N-term) (Cat. #AP4812a) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6UXN9
Other Accession Q8BFQ4, Q6NV31, Q5ZMV7, Q58E77, Q640J6
Reactivity Human
Predicted Xenopus, Chicken, Zebrafish, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35079 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 80335
Other Names WD repeat-containing protein 82, Protein TMEM113, Swd2, WDR82, TMEM113, WDR82A
Target/Specificity This WDR82 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human WDR82.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWDR82 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR82
Synonyms TMEM113, WDR82A
Function Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Cellular Location Nucleus Note=Associates with chromatin
Citations (0)

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WDR82 is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes.


Wu, M., et al. Mol. Cell. Biol. 28(24):7337-7344(2008)
Lee, J.H., et al. Mol. Cell. Biol. 28(2):609-618(2008)
Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)

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Cat# AP4812a
(40 western blots)
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