|Application ||WB, E|
|Calculated MW||46099 Da|
|Antigen Region||293-320 aa|
|Other Names||Kelch domain-containing protein 2, Hepatocellular carcinoma-associated antigen 33, Host cell factor homolog LCP, Host cell factor-like protein 1, HCLP-1, KLHDC2, HCA33|
|Target/Specificity||This KLDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the C-terminal region of human KLDC2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLDC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.|
|Tissue Location||Widely expressed, with high levels in skeletal muscle, heart, pancreas and liver. Undetectable in peripheral blood leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
KLDC2 represses CREB3-mediated transcription by interfering with CREB3-DNA binding.
Chin, K.T., et al. Mol. Cell. Biochem. 296 (1-2), 109-119 (2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)
Wang, Y., et al. J. Immunol. 169(2):1102-1109(2002)
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