|Application ||WB, E|
|Other Accession||P04176, P16331, Q2KIH7|
|Calculated MW||51862 Da|
|Antigen Region||132-161 aa|
|Other Names||Phenylalanine-4-hydroxylase, PAH, Phe-4-monooxygenase, PAH|
|Target/Specificity||This PAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from the Central region of human PAH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
Bonyadi, M., et al. Genet Test Mol Biomarkers 14(2):233-235(2010)
Dupuis, J., et al. Nat. Genet. 42(2):105-116(2010)
Santos, L.L., et al. Genet. Mol. Res. 9(1):1-8(2010)
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