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ANR49 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q8WVL7 |
| Other Accession | NP_060174 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 27290 Da |
| Antigen Region | 80-109 aa |
| Gene ID | 54851 |
|---|---|
| Other Names | Ankyrin repeat domain-containing protein 49, Fetal globin-inducing factor, ANKRD49, FGIF |
| Target/Specificity | This ANR49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the Central region of human ANR49. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ANR49 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ANKRD49 |
|---|---|
| Synonyms | FGIF |
| Function | Induces HBG1 expression (PubMed:16131492, PubMed:11162141). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q8VE42}. |
| Tissue Location | Widely expressed in fetus, at a high level in fetal liver, brain and lung. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Blau, C.A., et al. J. Biol. Chem. 280(44):36642-36647(2005)
Pitts, S.A., et al. Hum. Mol. Genet. 10(11):1155-1162(2001)
Yang, Y., et al. Blood Cells Mol. Dis. 27(1):1-15(2001)
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