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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LPPR4 Antibody (C-term)   

LPPR4 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LPPR4 Antibody  (C-term) AP4973b
    LPPR4 Antibody (C-term) (Cat. #AP4973b) western blot analysis in Hela,Jurkat,NCI-H460 cell line lysates (35ug/lane).This demonstrates the LPPR4 antibody detected the LPPR4 protein (arrow).
  • IHC-P - LPPR4 Antibody  (C-term) AP4973b
    LPPR4 Antibody (C-term) (Cat. #AP4973b) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LPPR4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - LPPR4 Antibody  (C-term) AP4973b
    LPPR4 Antibody (C-term) (Cat. #AP4973b) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z2D5
Other Accession Q7TME0, NP_055654
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 82983 Da
Antigen Region 666-695 aa
Additional Information
Gene ID 9890
Other Names Lipid phosphate phosphatase-related protein type 4, Brain-specific phosphatidic acid phosphatase-like protein 1, Plasticity-related gene 1 protein, PRG-1, LPPR4, KIAA0455, PRG1
Target/Specificity This LPPR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-695 amino acids from the C-terminal region of human LPPR4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLPPR4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LPPR4
Synonyms KIAA0455, PRG1
Function Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Specifically expressed in neurons.
Research Areas
Citations (0)

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LPPR4 belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting.


Trimbuch, T., et al. Cell 138(6):1222-1235(2009)
Vasan, R.S., et al. JAMA 302(2):168-178(2009)
Brauer, A.U., et al. Nat. Neurosci. 6(6):572-578(2003)

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$ 295.00
$ 99.00
Cat# AP4973b
(40 western blots)
Availability: In Stock
Bulk Size
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