|Calculated MW||39 KDa|
|Antigen Region||8-39 aa|
|Other Names||Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35, ANXA1, ANX1, LPC1|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.|
|Cellular Location||Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium. Found in the cytoplasm of type II pneumocytes and alveolar macrophages.|
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Provided below are standard protocols that you may find useful for product applications.
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
Wallner B.P.,et al.Nature 320:77-81(1986).
Kovacic R.T.,et al.Biochemistry 30:9015-9021(1991).
Arcone R.,et al.Eur. J. Biochem. 211:347-355(1993).
Varticovski L.,et al.Biochemistry 27:3682-3690(1988).
Biemann K.,et al.Science 237:992-998(1987).
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