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PHKB Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q93100 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 125124 Da |
| Antigen Region | 680-705 aa |
| Gene ID | 5257 |
|---|---|
| Other Names | Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta, PHKB |
| Dilution | WB~~1:500- 1:1000 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | PHKB |
|---|---|
| Function | Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation. |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
References
Wuellrich-Schmoll A.,et al.Eur. J. Biochem. 238:374-380(1996).
Beausoleil S.A.,et al.Nat. Biotechnol. 24:1285-1292(2006).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).
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