|Calculated MW||125124 Da|
|Antigen Region||680-705 aa|
|Other Names||Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta, PHKB|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
Wuellrich-Schmoll A.,et al.Eur. J. Biochem. 238:374-380(1996).
Beausoleil S.A.,et al.Nat. Biotechnol. 24:1285-1292(2006).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).
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