|Application ||WB, IHC-P, E|
|Calculated MW||56653 Da|
|Antigen Region||312-341 aa|
|Other Names||Keratin, type II cuticular Hb2, Keratin-82, K82, Type II hair keratin Hb2, Type-II keratin Kb22, KRT82, KRTHB2|
|Target/Specificity||This KRT82 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the Central region of human KRT82.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KRT82 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006) Rogers, M.A., et al. J. Invest. Dermatol. 124(3):536-544(2005)
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