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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   YTHDF1 Antibody   

YTHDF1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - YTHDF1 Antibody AP50608
    Western blot analysis of lysates from Hela cell line and human liver tissue lysate(from left to right),using YTHDF1 Antibody(AP50608). AP50608 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BYJ9
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 61,21 KDa
Antigen Region 3-31 aa
Additional Information
Gene ID 54915
Other Names YTH domain-containing family protein 1, Dermatomyositis associated with cancer putative autoantigen 1, DACA-1, YTHDF1, C20orf21
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name YTHDF1 (HGNC:15867)
Function Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non- coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A- containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440).
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.


Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
Onouchi H.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Daub H.,et al.Mol. Cell 31:438-448(2008).

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$ 295.00
Cat# AP50608
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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