|Application ||WB, IHC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||62 KDa|
|Antigen Region||430-459 aa|
|Other Names||BAG family molecular chaperone regulator 3, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, Docking protein CAIR-1, BAG3, BIS|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.|
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Provided below are standard protocols that you may find useful for product applications.
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.
Takayama S.,et al.J. Biol. Chem. 274:781-786(1999).
Lee J.H.,et al.Oncogene 18:6183-6190(1999).
Doong H.,et al.Oncogene 19:4385-4395(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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