|Application ||WB, IHC, IF|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||9 KDa|
|Antigen Region||2-35 aa|
|Other Names||Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2, HMGN2, HMG17|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation|
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Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation (By similarity).
Landsman D.,et al.J. Biol. Chem. 261:7479-7484(1986).
Landsman D.,et al.Nucleic Acids Res. 17:2301-2314(1989).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Giancotti V.,et al.Eur. J. Biochem. 198:211-216(1991).
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