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SNX4 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SNX4 Antibody AP50705
    Western blot analysis of lysate from HepG2 cell line,using SNX4 Antibody(AP50705). AP50705 was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O95219
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 52 KDa
Antigen Region 195-226 aa
Additional Information
Gene ID 8723
Other Names Sorting nexin-4, SNX4
Dilution WB~~1:500
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name SNX4 {ECO:0000303|PubMed:9819414, ECO:0000312|HGNC:HGNC:11175}
Function Involved in the regulation of endocytosis and in several stages of intracellular trafficking (PubMed:12668730, PubMed:17994011, PubMed:32513819, PubMed:33468622). Plays a role in recycling endocytosed transferrin receptor and prevent its degradation (PubMed:17994011). Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A (PubMed:32513819, PubMed:33468622).
Cellular Location Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also detected on a juxtanuclear endocytic recycling compartment (ERC).
Research Areas
Citations (0)
citation

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Background

May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.

References

Haft C.R.,et al.Mol. Cell. Biol. 18:7278-7287(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Traer C.J.,et al.Nat. Cell Biol. 9:1370-1380(2007).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).

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$ 350.00
Cat# AP50705
Size:
Quantity:
Availability: 2 weeks
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