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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AKR1C2 Antibody   

AKR1C2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - AKR1C2 Antibody AP50743
    Western blot analysis of lysate from A549 cell line,using AKR1C2 Antibody(AP50743). AP50743 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P52895
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 38,16 KDa
Antigen Region 34-63 aa
Additional Information
Gene ID 1646
Other Names Aldo-keto reductase family 1 member C2, 1---, 3-alpha-HSD3, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, DD-2, DD2, Dihydrodiol dehydrogenase/bile acid-binding protein, DD/BABP, Trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, Type III 3-alpha-hydroxysteroid dehydrogenase, AKR1C2, DDH2
Dilution WB~~1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name AKR1C2
Synonyms DDH2
Function Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha- DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
Cellular Location Cytoplasm.
Tissue Location Expressed in fetal testes. Expressed in fetal and adult adrenal glands.
Research Areas
Citations (0)

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Background

Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha- DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.

References

Qin K.-N.,et al.J. Steroid Biochem. Mol. Biol. 46:673-679(1993).
Ciaccio P.J.,et al.Biochim. Biophys. Acta 1186:129-132(1994).
Qin K.-N.,et al.Gene 149:357-361(1994).
Dufort I.,et al.Biochem. Biophys. Res. Commun. 228:474-479(1996).
Shiraishi H.,et al.Biochem. J. 334:399-405(1998).

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$ 295.00
Cat# AP50743
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
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