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KCNT1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q5JUK3 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 138,142,140 KDa |
| Antigen Region | 1035-1061 aa |
| Gene ID | 57582 |
|---|---|
| Other Names | Potassium channel subfamily T member 1, KCa41, KCNT1, KIAA1422 |
| Dilution | WB~~ 1:1000 IHC~~1:50-100 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | KCNT1 |
|---|---|
| Synonyms | KIAA1422 |
| Function | Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity).
References
Humphray S.J.,et al.Nature 429:369-374(2004).
Nagase T.,et al.DNA Res. 7:65-73(2000).
Heron S.E.,et al.Nat. Genet. 44:1188-1190(2012).
Barcia G.,et al.Nat. Genet. 44:1255-1259(2012).
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