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KCNT1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - KCNT1 Antibody AP50772
    Western blot analysis of lysate from human brain tissue lysate,using KCNT1 Antibody(AP50772). AP50772 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • IHC - KCNT1 Antibody AP50772
    Immunohistochemistry analysis of paraffin-embedded human brain tissue using KCNT1 antibody.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q5JUK3
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 138,142,140 KDa
Antigen Region 1035-1061 aa
Additional Information
Gene ID 57582
Other Names Potassium channel subfamily T member 1, KCa41, KCNT1, KIAA1422
Dilution WB~~ 1:1000
IHC~~1:50-100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name KCNT1
Synonyms KIAA1422
Function Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle
Research Areas
Citations (0)

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Background

Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity).

References

Humphray S.J.,et al.Nature 429:369-374(2004).
Nagase T.,et al.DNA Res. 7:65-73(2000).
Heron S.E.,et al.Nat. Genet. 44:1188-1190(2012).
Barcia G.,et al.Nat. Genet. 44:1255-1259(2012).

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$ 295.00
Cat# AP50772
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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