|Calculated MW||34 KDa|
|Antigen Region||128-153 aa|
|Other Names||Zinc transporter ZIP1, Solute carrier family 39 member 1, Zinc-iron-regulated transporter-like, Zrt- and Irt-like protein 1, ZIP-1, hZIP1, SLC39A1, IRT1, ZIP1, ZIRTL|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Synonyms||IRT1, ZIP1, ZIRTL|
|Function||Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.|
|Cellular Location||Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines|
|Tissue Location||Ubiquitous. Expressed in most adult and fetal tissues including the epidermis.|
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Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.
Lioumi M.,et al.Genomics 62:272-280(1999).
Milon B.,et al.FEBS Lett. 507:241-246(2001).
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
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