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CREBL1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • IHC-P - CREBL1 Antibody (C-term) AP5101b
    Immunohistochemical analysis of paraffin-embedded H. prostate section using CREBL1 Antibody (C-term)(Cat#AP5101b). AP5101b was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • IHC-P - CREBL1 Antibody (C-term) AP5101b
    Immunohistochemical analysis of paraffin-embedded H. kidney section using CREBL1 Antibody (C-term)(Cat#AP5101b). AP5101b was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • WB - CREBL1 Antibody (C-term) AP5101b
    Western blot analysis of lysates from Hela, HepG2 cell line and human placenta tissue lysate (from left to right), using CREBL1Antibody (C-term) (Cat. #AP5101b). AP5101b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • WB - CREBL1 Antibody (C-term) AP5101b
    CREBL1 Antibody (C-term) (Cat. #AP5101b) western blot analysis in mouse NIH-3T3,CHO cell line and mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CREBL1 antibody detected the CREBL1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99941
Reactivity Human, Hamster, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 76709 Da
Antigen Region 560-589 aa
Additional Information
Gene ID 1388
Other Names Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein, Creb-rp, cAMP-responsive element-binding protein-like 1, Processed cyclic AMP-dependent transcription factor ATF-6 beta, ATF6B, CREBL1, G13
Target/Specificity This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1.
Dilution IHC-P~~1:25
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCREBL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATF6B
Synonyms CREBL1, G13
Function Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.


Guan, D., et al. J. Cell. Biochem. 108(4):825-831(2009)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009)
Thuerauf, D.J., et al. J. Biol. Chem. 279(20):21078-21084(2004)

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$ 295.00
$ 99.00
Cat# AP5101b
(40 western blots)
Availability: In Stock
Bulk Size
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