|Reactivity||Human, Mouse, Rat|
|Calculated MW||78, 75, 82 KDa|
|Antigen Region||261 - 320 aa|
|Other Names||Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor, FSHR, LGR1|
|Target/Specificity||KLH conjugated synthetic peptide derived from human FSHR|
|Format||0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Induces cAMP production through the activation of PI3K-AKT and SRC-ERK1/2 signaling pathways.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Sertoli cells and ovarian granulosa cells.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Minegish T.,et al.Biochem. Biophys. Res. Commun. 175:1125-1130(1991).
Tilly J.L.,et al.Endocrinology 131:799-806(1992).
Kelton C.A.,et al.Mol. Cell. Endocrinol. 89:141-151(1992).
Liu X.,et al.Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
Kopatz S.A.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
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