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Histone H2B Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Histone H2B Antibody AP51253
    All lanes : Anti-Histone H2B Antibody at 1:1000 dilution Lane 1: A549 whole cell lysates Lane 2: WiDr whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 14 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P57053
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 14 KDa
Additional Information
Gene ID 102724334
Other Names Histone H2B type F-S, Histone H2Bs, H2B/s, H2BFS
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name H2BFS
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular Location Nucleus. Chromosome.
Citations (0)

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Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

References

Shimizu N.,et al.Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Hattori M.,et al.Nature 405:311-319(2000).
Kim H.S.,et al.J. Immunol. 168:2356-2364(2002).
Frohm M.,et al.Eur. J. Biochem. 237:86-92(1996).
Tollin M.,et al.Peptides 24:523-530(2003).

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$ 295.00
Cat# AP51253
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
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