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Kv3.4 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Kv3.4 Antibody AP51299
    Anti-Kv3.4 Antibodyat 1:1000 dilution + K562 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 70 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q03721
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 70 KDa
Antigen Region 1 - 60 aa
Additional Information
Gene ID 3749
Other Names Potassium voltage-gated channel subfamily C member 4, KSHIIIC, Voltage-gated potassium channel subunit Kv34, KCNC4
Target/Specificity KLH conjugated synthetic peptide derived from human Kv3.4
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name KCNC4 (HGNC:6236)
Function This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)
citation

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Background

This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

References

de Miera E.V.-S.,et al.Proc. R. Soc. B 248:9-18(1992).
Gregory S.G.,et al.Nature 441:315-321(2006).
Covarrubias M.,et al.Neuron 13:1403-1412(1994).
Beck E.J.,et al.J. Gen. Physiol. 112:71-84(1998).
Antz C.,et al.Nature 385:272-275(1997).

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$ 350.00
Cat# AP51299
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Availability: 2 weeks
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