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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PDE4B/C/D Antibody   

PDE4B/C/D Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PDE4B/C/D Antibody AP51417
    Anti-PDE4B/C/D Antibodyat 1:1000 dilution + HepG2 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 83 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q07343
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 80 KDa
Additional Information
Gene ID 5142
Other Names cAMP-specific 3', 5'-cyclic phosphodiesterase 4B, DPDE4, PDE32, PDE4B, DPDE4
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name PDE4B
Synonyms DPDE4
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Tissue Location Expressed in brain, heart, lung and skeletal muscle
Research Areas
Citations (0)

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Background

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.

References

Obernolte R.,et al.Gene 129:239-247(1993).
Bolger G.,et al.Mol. Cell. Biol. 13:6558-6571(1993).
Huston E.,et al.Biochem. J. 328:549-558(1997).
McLaughlin M.M.,et al.J. Biol. Chem. 268:6470-6476(1993).
Cheung Y.F.,et al.J. Pharmacol. Exp. Ther. 322:600-609(2007).

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$ 295.00
Cat# AP51417
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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