|Reactivity||Human, Mouse, Rat|
|Calculated MW||50 KDa|
|Other Names||Ataxin-10, Brain protein E46 homolog, Spinocerebellar ataxia type 10 protein, ATXN10, SCA10|
|Format||0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.|
|Cellular Location||Cytoplasm, perinuclear region|
|Tissue Location||Expressed in the central nervous system.|
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Provided below are standard protocols that you may find useful for product applications.
Necessary for the survival of cerebellar neurons (By similarity). Induces neuritogenesis by activating the Ras-MAP kinase pathway (By similarity). May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis (By similarity).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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