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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   COPZ2 Antibody (C-term)   

COPZ2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - COPZ2 Antibody (C-term) AP5175b
    Western blot analysis of COPZ2 Antibody (C-term) (Cat. #AP5175b) in mouse spleen tissue lysates (35ug/lane).COPZ2 (arrow) was detected using the purified Pab.
  • IHC-P - COPZ2 Antibody (C-term) AP5175b
    COPZ2 Antibody (C-term) (Cat. #AP5175b) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the COPZ2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - COPZ2 Antibody (C-term) AP5175b
    COPZ2 Antibody (C-term) (Cat. #AP5175b) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P299
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23548 Da
Antigen Region 156-184 aa
Additional Information
Gene ID 51226
Other Names Coatomer subunit zeta-2, Zeta-2-coat protein, Zeta-2 COP, COPZ2
Target/Specificity This COPZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the C-terminal region of human COPZ2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCOPZ2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COPZ2
Function The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
Cellular Location Cytoplasm. Endoplasmic reticulum-Golgi intermediate compartment membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Shows a significant preference for ERGIC and cis-Golgi apparatus compared with trans-Golgi network
Research Areas
Citations (0)

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COPZ2 encodes a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. COPZ2 is similar to a related family member, and the two encoded proteins form distinct isotypes of the coatomer protein complex.


Yu, W., et al. J. Mol. Biol. 386(4):903-912(2009)
Wegmann, D., et al. Mol. Cell. Biol. 24(3):1070-1080(2004)
Futatsumori, M., et al. J. Biochem. 128(5):793-801(2000)

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Cat# AP5175b
(40 western blots)
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