YEATS2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9ULM3 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 150 KDa |
Antigen Region | 331 - 390 aa |
Gene ID | 55689 |
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Other Names | YEATS domain-containing protein 2, YEATS2, KIAA1197 |
Target/Specificity | KLH conjugated synthetic peptide derived from human YEATS2 |
Dilution | WB~~ 1:1000 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | YEATS2 (HGNC:25489) |
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Function | Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (PubMed:18838386, PubMed:19103755, PubMed:27103431). YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) (PubMed:27103431). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:27103431). |
Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
References
Nagase T.,et al.DNA Res. 6:337-345(1999).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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