C7orf47 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | Q8TAP8 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27953 Da |
Antigen Region | 41-69 aa |
Gene ID | 221908 |
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Other Names | Protein phosphatase 1 regulatory subunit 35, PPP1R35, C7orf47 |
Target/Specificity | This C7orf47 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-69 amino acids from the N-terminal region of human C7orf47. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | C7orf47 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPP1R35 (HGNC:28320) |
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Function | During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with RTTN, leading to the centriole to centrosome conversion (PubMed:30168418, PubMed:30230954). In addition, may play a role in the primary cilia assembly (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Recruited to the nascent daughter centriole early in the duplication cycle and localizes to the proximal centriolar lumen just above the cartwheel (PubMed:30168418, PubMed:30230954). Co-localizes with RTTN at the centriole (PubMed:30168418) |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein has not been specifically defined.
References
Scherer, S.W., et al. Science 300(5620):767-772(2003)
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