|Application ||WB, E|
|Calculated MW||22689 Da|
|Antigen Region||57-85 aa|
|Other Names||CMRF35-like molecule 7, CLM-7, CD300 antigen-like family member B, CMRF35-A2, Immune receptor expressed on myeloid cells 3, IREM-3, Leukocyte mono-Ig-like receptor 5, Triggering receptor expressed on myeloid cells 5, TREM-5, CD300b, CD300LB, CD300B, CLM7, CMRF35A2, IREM3, LMIR5, TREM5|
|Target/Specificity||This CD300LB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human CD300LB.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CD300LB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD300B, CLM7, CMRF35A2, IREM3, LMIR5, TR|
|Function||Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed exclusively in myeloid lineages.|
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Provided below are standard protocols that you may find useful for product applications.
CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006.
Yamanishi, Y., et al. Blood 111(2):688-698(2008)
Martinez-Barriocanal, A., et al. J. Immunol. 177(5):2819-2830(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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