|Application ||WB, E|
|Calculated MW||22689 Da|
|Antigen Region||57-85 aa|
|Other Names||CMRF35-like molecule 7, CLM-7, CD300 antigen-like family member B, CMRF35-A2, Immune receptor expressed on myeloid cells 3, IREM-3, Leukocyte mono-Ig-like receptor 5, Triggering receptor expressed on myeloid cells 5, TREM-5, CD300b, CD300LB, CD300B, CLM7, CMRF35A2, IREM3, LMIR5, TREM5|
|Target/Specificity||This CD300LB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human CD300LB.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CD300LB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD300B, CLM7, CMRF35A2, IREM3, LMIR5, TR|
|Function||Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed exclusively in myeloid lineages.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006.
Yamanishi, Y., et al. Blood 111(2):688-698(2008)
Martinez-Barriocanal, A., et al. J. Immunol. 177(5):2819-2830(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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