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>   home   >   Products   >   Primary Antibodies   >   Rabbit Anti-LDL receptor Polyclonal Antibody   

Rabbit Anti-LDL receptor Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Rabbit Anti-LDL receptor Polyclonal Antibody AP52062
    Human colon lysates probed with Anti LDL Receptor Polyclonal Antibody, Unconjugated (AP52062) at 1:200 overnight at 4˚C. Followed by conjugation to secondary antibody at 1:3000 for 90 min at 37˚C.
  • IHC-P - Rabbit Anti-LDL receptor Polyclonal Antibody AP52062
    Formalin-fixed and paraffin embedded human rectal carcinoma labeled Anti-LDL receptor Polyclonal Antibody, Unconjugated (AP52062) at 1:200, followed by conjugation to the secondary antibody and DAB staining
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, IHC-P
Primary Accession P01130
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 95376 Da
Additional Information
Gene ID 3949
Other Names FH; FHC; LDLCQ2; Low-density lipoprotein receptor; LDL receptor; LDLR
Dilution WB~~1:100~1:500
IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name LDLR
Function Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
Cellular Location Cell membrane; Single-pass type I membrane protein. Endomembrane system; Single-pass type I membrane protein Membrane, clathrin-coated pit; Single-pass type I membrane protein. Golgi apparatus. Early endosome. Late endosome. Cell surface. Lysosome. Note=Found distributed from the plasma membrane to intracellular compartments. Localizes to the Golgi apparatus, early and late endosomes/lysosomes and cell surface in the presence of PCSK9
Citations (0)

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Background

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

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$ 295.00
Cat# AP52062
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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