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CMPK2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CMPK2 Antibody (Center) AP5206c
    Western blot analysis of CMPK2 Antibody (Center) (Cat. #AP5206c) in Hela cell line lysates (35ug/lane).CMPK2 (arrow) was detected using the purified Pab.
  • IHC-P - CMPK2 Antibody (Center) AP5206c
    CMPK2 Antibody (Center) (Cat. #AP5206c) IHC analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CMPK2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - CMPK2 Antibody (Center) AP5206c
    CMPK2 Antibody (Center) (Cat. #AP5206c) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5EBM0
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49448 Da
Antigen Region 142-170 aa
Additional Information
Gene ID 129607
Other Names UMP-CMP kinase 2, mitochondrial, Nucleoside-diphosphate kinase, CMPK2
Target/Specificity This CMPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-170 amino acids from the Central region of human CMPK2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCMPK2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CMPK2
Function May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs. Also displays broad nucleoside diphosphate kinase activity.
Cellular Location Mitochondrion.
Tissue Location Among all investigated tumors, leukemia cells show the most abundant expression.
Citations (0)

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Mitochondrial UMP-CMP kinase (EC is a component of the salvage pathway for nucleotide synthesis. Other enzymes of the salvage pathway include thymidine kinase-2 (TK2; MIM 188250), deoxynucleotidase-2 (NT5M; MIM 605292), deoxyguanosine kinase (DGUOK; MIM 601465), adenylate kinase-2 (AK2; MIM 103020), adenylate kinase-3 (AK3; MIM 609290), adenylate kinase-3-like-1 (AK3L1; MIM 103030), and nucleoside diphosphate kinase.


Xu, Y., et al. J. Biol. Chem. 283(3):1563-1571(2008)

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$ 295.00
$ 99.00
Cat# AP5206c
(40 western blots)
Availability: In Stock
Bulk Size
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