Rabbit Anti-WNT2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF, IHC-P |
---|---|
Primary Accession | P09544 |
Reactivity | Human, Mouse, Rat, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 40418 Da |
Gene ID | 7472 |
---|---|
Other Names | IRP; INT1L1; Protein Wnt-2; Int-1-like protein 1; Int-1-related protein; WNT2 |
Dilution | WB~~1:100~1:500 IHC-P~~1:100~1:500 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | WNT2 |
---|---|
Synonyms | INT1L1, IRP |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20018874). Functions as a upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). |
Cellular Location | Secreted, extracellular space, extracellular matrix. Secreted |
Tissue Location | Expressed in brain in the thalamus, in fetal and adult lung and in placenta. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
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