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>   home   >   Products   >   Primary Antibodies   >   Rabbit Anti-WNT2 Polyclonal Antibody   

Rabbit Anti-WNT2 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Rabbit Anti-WNT2 Polyclonal Antibody AP52104
    Mouse brain lysates probed with Anti-WNT2 Polyclonal Antibody, Unconjugated (AP52104) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 90min in 37˚C.
    detail
  • IHC-P - Rabbit Anti-WNT2 Polyclonal Antibody AP52104
    Formalin-fixed and paraffin embedded human placenta labeled with Anti-WNT2 Polyclonal Antibody, Unconjugated (AP52104) at 1:200 followed by conjugation to the secondary antibody and DAB staining
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, IHC-P
Primary Accession P09544
Reactivity Human, Mouse, Rat, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 40418 Da
Additional Information
Gene ID 7472
Other Names IRP; INT1L1; Protein Wnt-2; Int-1-like protein 1; Int-1-related protein; WNT2
Dilution WB~~1:100~1:500
IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name WNT2
Synonyms INT1L1, IRP
Function Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20018874). Functions as a upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix. Secreted
Tissue Location Expressed in brain in the thalamus, in fetal and adult lung and in placenta.
Citations (0)
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Background

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.

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Discontinued
Cat# AP52104
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