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>   home   >   Products   >   Primary Antibodies   >   Rabbit Anti-CD68 Polyclonal Antibody   

Rabbit Anti-CD68 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Rabbit Anti-CD68 Polyclonal Antibody AP52189
    A549 cell lysates probed with Anti-CD68 Polyclonal Antibody, Unconjugated (AP52189) at 1:300 overnight at 4˚C. Followed by conjugation to secondary antibody at 1:5000 for 90 min at 37˚C.
  • IHC-P - Rabbit Anti-CD68 Polyclonal Antibody AP52189
    Formalin-fixed and paraffin embedded rat myocardium labeled with Anti-MuRF1/Trim63 Polyclonal Antibody, Unconjugated (AP52189) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
  • IF - Rabbit Anti-CD68 Polyclonal Antibody AP52189
    Formalin-fixed and rat colitis tissue labeled with Anti-CD68 Polyclonal Antibody, Unconjugated AP52189 at 1:200 followed by conjugation to the secondary antibody, Goat Anti-Rabbit IgG, Cy5 conjugated,
  • SPECIFICATION
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IHC-P
Primary Accession P31996
Reactivity Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 34818 Da
Additional Information
Gene ID 12514
Other Names Lamp4; gp11; Scard1; Macrosialin; CD68
Dilution WB~~1:100~1:500
IHC-P~~1:100~1:500
IF~~1:100~1:200
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name Cd68
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Cellular Location Isoform Long: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein
Tissue Location Expressed in tissue macrophages and to a lesser extent in dendritic cells
Citations ( 0 )

Background

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

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$ 295.00
Cat# AP52189
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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