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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   FBXL15 Antibody (C-term)   

FBXL15 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - FBXL15 Antibody (C-term) AP5221B
    FBXL15 Antibody (C-term) (Cat. #AP5221b) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL15 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • WB - FBXL15 Antibody (C-term) AP5221B
    Western blot analysis of FBXL15 Antibody (C-term) (RB26324) in MDA-MB435 cell line lysates (35ug/lane).FBXL15 (arrow) was detected using the purified Pab.
  • WB - FBXL15 Antibody (C-term) AP5221B
    Western blot analysis of FBXL15 Antibody (C-term) (Cat. #AP5221b) in mouse kidney tissue lysates (35ug/lane).FBXL15 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H469
Other Accession D4ABB4, Q91W61, E1BNS0
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32998 Da
Antigen Region 252-280 aa
Additional Information
Gene ID 79176
Other Names F-box/LRR-repeat protein 15, F-box only protein 37, FBXL15, FBXO37
Target/Specificity This FBXL15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the C-terminal region of human FBXL15.
Dilution IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFBXL15 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXL15
Synonyms FBXO37
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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FBXL15 is probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.


Deloukas, P., et al. Nature 429(6990):375-381(2004)

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Cat# AP5221B
(40 western blots)
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