|Application ||WB, IF, ICC, IHC-P|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||50433 Da|
|Other Names||CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III; TUBB3|
|Format||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce|
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.|
|Function||Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.|
|Cellular Location||Cytoplasm, cytoskeleton.|
|Tissue Location||Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues.|
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Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
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