|Application ||WB, IHC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||265554 Da|
|Other Names||Acetyl-CoA carboxylase 1, ACC1, ACC-alpha, Biotin carboxylase, ACACA, ACAC, ACC1, ACCA|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Synonyms||ACAC, ACC1, ACCA|
|Function||Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.|
|Tissue Location||Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Abu-Elheiga L.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:4011-4015(1995).
Mao J.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:7515-7520(2003).
Sinilnikova O.M.,et al.Carcinogenesis 25:2417-2424(2004).
Travers M.T.,et al.Biochim. Biophys. Acta 1634:97-106(2003).
Travers M.T.,et al.Genomics 85:71-84(2005).
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