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NPFF Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | O15130 |
| Other Accession | Q9WVA9, Q9WVA8, Q9TUX7 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 12440 Da |
| Antigen Region | 86-113 aa |
| Gene ID | 8620 |
|---|---|
| Other Names | Pro-FMRFamide-related neuropeptide FF, FMRFamide-related peptides, Neuropeptide SF, NPSF, Neuropeptide FF, NPFF, Neuropeptide AF, NPAF, NPFF |
| Target/Specificity | This NPFF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-113 amino acids from the C-terminal region of human NPFF. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NPFF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NPFF |
|---|---|
| Function | Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL encodes a preproprotein which is cleaved to form two active peptides with similar function.
References
Yang, H.Y., et al. Neuropeptides 42(1):1-18(2008)
Roumy, M., et al. J. Biol. Chem. 282(11):8332-8342(2007)
Anko, M.L., et al. J. Neurochem. 96(2):573-584(2006)
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