|Calculated MW||56 KDa|
|Other Names||BOP;CD8 beta opposite;CD8b opposite;Histone lysine N methyltransferase SMYD1;KMT3D;SET and MYND domain-containing protein 1;SMYD1;SMYD1_HUMAN;Zinc finger MYND domain containing 18;ZMYND18;ZMYND22;zinc finger, MYND domain containing 18.|
|Format||Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50% glycerol|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Expression seems mostly restricted to heart and skeletal muscle.|
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Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Hillier L.W.,et al.Nature 434:724-731(2005).
Li D.,et al.Nucleic Acids Res. 37:7059-7071(2009).
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