|Calculated MW||37 KDa|
|Other Names||CALU;CALU_HUMAN;Calumenin 1;Calumenin 2;Calumenin;Crocalbin;crocalbin-like protein; FLJ90608;IEF SSP 9302;multiple EF-hand protein;OTTHUMP00000212712;OTTHUMP00000212713; OTTHUMP00000212714;OTTHUMP00000212715.|
|Format||Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50% glycerol|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.|
|Tissue Location||Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver|
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Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).
Vorum H.,et al.Biochim. Biophys. Acta 1386:121-131(1998).
Yabe D.,et al.Genomics 49:331-333(1998).
Peterson R.E. Jr.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Wang Q.,et al.Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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