TTC26 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | A0AVF1 |
Other Accession | Q5U2N8, Q8BS45, Q4R7Z9, NP_079202.2 |
Reactivity | Human |
Predicted | Monkey, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 64178 Da |
Antigen Region | 467-496 aa |
Gene ID | 79989 |
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Other Names | Intraflagellar transport protein 56, TTC26 (HGNC:21882) |
Target/Specificity | This TTC26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-496 amino acids from the C-terminal region of human TTC26. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TTC26 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IFT56 (HGNC:21882) |
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Synonyms | TTC26 |
Function | Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme. |
Cellular Location | Cell projection, cilium {ECO:0000250|UniProtKB:Q8BS45}. Note=Localizes at the base to the ciliary transition zone. {ECO:0000250|UniProtKB:Q8BS45} |
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Provided below are standard protocols that you may find useful for product applications.
References
Suzuki, Y., et al. Genome Res. 14(9):1711-1718(2004)
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