|Application ||WB, FC, E|
|Other Accession||Q9CPP0, NP_008924.1|
|Calculated MW||19344 Da|
|Antigen Region||30-58 aa|
|Other Names||Nucleoplasmin-3, NPM3|
|Target/Specificity||This NPM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human NPM3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NPM3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a chaperone.|
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Provided below are standard protocols that you may find useful for product applications.
NPM3 is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. This protein is strongly expressed in diverse cell types where it localizes primarily to the nucleus. Based on its similarity to nucleoplasmin and nucleophosmin, this protein likely functions as a molecular chaperone in the cell nucleus.
Gadad, S.S., et al. Biochemistry 49(7):1355-1357(2010)
Pradeepa, M.M., et al. J. Biol. Chem. 284(43):29956-29967(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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