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Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB, IF, IP |
|---|---|
| Primary Accession | P11021 |
| Other Accession | NM_005347 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Immunogen | Purified recombinant human BiP/GRP78 protein expressed in E.coli. |
| Purification | Affinity purified |
| Calculated MW | 78 KDa |
| Gene ID | 3309 |
|---|---|
| Other Names | 78 kDa glucose regulated protein;78 kDa glucose-regulated protein;AL022860;AU019543;BIP;D2Wsu141e;D2Wsu17e;Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78;Endoplasmic reticulum lumenal Ca2+ binding protein grp78;FLJ26106;Glucose Regulated Protein 78kDa;GRP 78;GRP-78;GRP78;GRP78_HUMAN;Heat shock 70 kDa protein 5;Heat Shock 70kDa Protein 5;Hsce70;HSPA 5;HSPA5;Immunoglobulin Heavy Chain Binding Protein;Immunoglobulin heavy chain-binding protein;mBiP;MIF2;Sez7. |
| Dilution | WB~~1:1000 |
| Format | PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | HSPA5 |
|---|---|
| Synonyms | GRP78 |
| Function | Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate. |
| Cellular Location | Endoplasmic reticulum lumen. Melanosome. Cytoplasm Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
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Background
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate
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