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Anti-HDAC6 Antibody

Mouse Monoclonal Antibody

     
  • WB - Anti-HDAC6 Antibody AP53478
    Western blot detection of HDAC6 in T47D,Jurkat CHO-K1(B) and CHO-K1 transfected by HDAC6-fragment EGFP fusion protein(A)cell lysates using HDAC6 mouse mAb (1:1000 diluted).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9UBN7
Other Accession NM_006044
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype lgG2a
Immunogen Purified recombinant human HDAC6 protein expressed in E.coli.
Purification Affinity purified
Calculated MW 160KDa
Additional Information
Gene ID 10013
Other Names FLJ16239 ;HD 6 ;HD6 ;HDAC 6 ;HDAC6 ;HDAC6_HUMAN ;Histone deacetylase 6 (HD6) ;Histone deacetylase 6 ;JM 21 ;JM21 ;KIAA0901 ;OTTHUMP00000032398 ;OTTHUMP00000197663
Dilution WB~~1:1000
Format Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name HDAC6
Synonyms KIAA0901
Function Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Cellular Location Nucleus. Cytoplasm. Perikaryon. Cell projection, dendrite. Cell projection, axon. Note=It is mainly cytoplasmic, where it is associated with microtubules
Research Areas
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Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progr

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$ 295.00
Cat# AP53478
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
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