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SYT13 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q7L8C5 |
| Other Accession | NP_065877.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46885 Da |
| Antigen Region | 25-52 aa |
| Gene ID | 57586 |
|---|---|
| Other Names | Synaptotagmin-13, Synaptotagmin XIII, SytXIII, SYT13, KIAA1427 |
| Target/Specificity | This SYT13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human SYT13. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SYT13 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SYT13 |
|---|---|
| Synonyms | KIAA1427 |
| Function | May be involved in transport vesicle docking to the plasma membrane. |
| Cellular Location | Membrane; Single-pass membrane protein |
| Tissue Location | Expressed in brain, pancreas and kidney. |
Provided below are standard protocols that you may find useful for product applications.
Background
SYT13 belongs to the large synaptotagmin protein family. All synaptotagmins show type I membrane topology, with an extracellular N terminus, a single transmembrane region, and a cytoplasmic C terminus containing tandem C2 domains. Major functions of synaptotagmins include vesicular traffic, exocytosis, and secretion.
References
Jahn, J.E., et al. Int. J. Oncol. 32(2):441-449(2008)
Craxton, M. Genomics 77 (1-2), 43-49 (2001) :
Fukuda, M., et al. Biochem. J. 354 (PT 2), 249-257 (2001) :
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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