CTTB2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q8WZ74 |
Other Accession | Q2IBD4, NP_219499.1, Q2QLA2 |
Reactivity | Human |
Predicted | Horse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 181051 Da |
Antigen Region | 72-100 aa |
Gene ID | 83992 |
---|---|
Other Names | Cortactin-binding protein 2, CortBP2, CTTNBP2, C7orf8, CORTBP2, KIAA1758 |
Target/Specificity | This CTTB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the N-terminal region of human CTTB2. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CTTB2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CTTNBP2 |
---|---|
Synonyms | C7orf8, CORTBP2, KIAA1758 |
Function | Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance. |
Cellular Location | Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation. |
Tissue Location | Highest expression in brain. Also expressed in kidney, pancreas, lung, heart, liver, skeletal muscle and placenta |
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Provided below are standard protocols that you may find useful for product applications.
Background
CTTB2 is a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat interacts with a central regulator of the actin cytoskeleton. [provided by RefSeq].
References
Zink, D., et al. J. Cell Biol. 166(6):815-825(2004)
Cheung, J., et al. Genomics 78 (1-2), 7-11 (2001)
Ohoka, Y., et al. Genes Cells 3(9):603-612(1998)
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