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CTTB2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CTTB2 Antibody (N-term) AP5490a
    CTTB2 Antibody (N-term) (Cat.#AP5490a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CTTB2 antibody detected the CTTB2 protein (arrow).
  • IHC-P - CTTB2 Antibody (N-term) AP5490a
    CTTB2 Antibody (N-term) (Cat. #AP5490a) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CTTB2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q8WZ74
Other Accession Q2IBD4, NP_219499.1, Q2QLA2
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 181051 Da
Antigen Region 72-100 aa
Additional Information
Gene ID 83992
Other Names Cortactin-binding protein 2, CortBP2, CTTNBP2, C7orf8, CORTBP2, KIAA1758
Target/Specificity This CTTB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the N-terminal region of human CTTB2.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTTB2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTTNBP2
Synonyms C7orf8, CORTBP2, KIAA1758
Function Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
Cellular Location Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation
Tissue Location Highest expression in brain. Also expressed in kidney, pancreas, lung, heart, liver, skeletal muscle and placenta.
Research Areas
Citations (0)

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Background

CTTB2 is a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat interacts with a central regulator of the actin cytoskeleton. [provided by RefSeq].

References

Zink, D., et al. J. Cell Biol. 166(6):815-825(2004)
Cheung, J., et al. Genomics 78 (1-2), 7-11 (2001)
Ohoka, Y., et al. Genes Cells 3(9):603-612(1998)

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Cat# AP5490a
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(40 western blots)
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