- CITATIONS: 2
|Application ||WB, FC, E|
|Other Accession||C9JPN9, D6RA61, D6R901, D6RJB6, D6RCP7, D6R9N7, D6RBQ6, C9J2P7, C9JLJ4, C9JVI0, A8MUK1, XP_001130410.1|
|Calculated MW||59711 Da|
|Antigen Region||496-524 aa|
|Other Names||Ubiquitin carboxyl-terminal hydrolase 17-like protein 24, Deubiquitinating enzyme 17, Ubiquitin thioesterase 17, Ubiquitin-specific-processing protease 17, USP17L24|
|Target/Specificity||This USP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-524 amino acids from the C-terminal region of human USP17.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UBP17 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.|
|Cellular Location||Nucleus, nucleolus. Endoplasmic reticulum|
|Tissue Location||Expressed in heart, brain, liver and skeletal muscle.|
Provided below are standard protocols that you may find useful for product applications.
USP17 recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins (By similarity).
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