|Application ||WB, FC, E|
|Calculated MW||34906 Da|
|Antigen Region||17-45 aa|
|Other Names||Transmembrane protein 165, Transmembrane protein PT27, Transmembrane protein TPARL, TMEM165, TPARL|
|Target/Specificity||This TM165 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human TM165.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TM165 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as a calcium/proton transporter involved in calcium and in lysosomal pH homeostasis. Therefore, it may play an indirect role in protein glycosylation.|
|Cellular Location||Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans- Golgi network membrane. Lysosome membrane. Early endosome membrane. Late endosome membrane|
|Tissue Location||Ubiquitously expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The function of TM165 remains unknown.
Terracciano, A., et al. Mol. Psychiatry (2008)
Hu, R.M., et al. Proc. Natl. Acad. Sci. U.S.A. 97(17):9543-9548(2000)
Akagi, J., et al. Biochem. Biophys. Res. Commun. 157(2):548-557(1988)
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